926 quotes from books that matter
Medicine 3.0 asks, what is the “best” mix of fats for our patient? I use an expanded lipid panel to keep track of how changes in fatty acid consumption may affect my patients’ cholesterol synthesis and reabsorption, and their overall lipid and inflammatory response.
Given that population growth requires babies not just to be born, but to grow up to have their own babies, getting appropriate safety protocols would take decades, even if we unethically began doing experiments on humans starting tomorrow.
It wasn’t an easy problem to solve. Rosenberg tried one approach after another, without success. A cancer “vaccine” went nowhere. He spent many years experimenting with interleukin-2 (IL-2), a cytokine that plays a major role in the immune response (it basically amplifies the activity of lymphocytes, white blood cells that fight infection).
The real issue is that neither side has perfect information going to the table. This often means you don’t know enough to open with confidence.
Your brain has far more neural circuitry allocated for wanting rewards than for liking them. The wanting centers in the brain are large: the brain stem, the nucleus accumbens, the ventral tegmental area, the dorsal striatum, the amygdala, and portions of the prefrontal cortex.
Never be so sure of what you want that you wouldn’t take something better.
At some point, our primate ancestors underwent a random genetic mutation that effectively switched on their ability to turn fructose into fat: the gene for the uricase enzyme was “silenced,” or lost.
Your genes are operating beneath the surface of every habit. Indeed, beneath the surface of every behavior.
Pay attention to their usage of pronouns. The more in love they are with “I,” “me,” and “my” the less important they are. Conversely, the harder it is to get a first person pronoun out of a negotiator’s mouth, the more important they are.
Having more muscle mass on your exoskeleton appears to protect you from all kinds of trouble, even adverse outcomes following surgery—but most important, it is highly correlated with a lower risk of falling, a leading but oft-ignored cause of death and disability in the elderly.
As always, tone of voice, respectful and deferential, is critical. Otherwise, treat 'why' like a burner on a hot stove—don’t touch it.
The language of negotiation is primarily a language of conversation and rapport: a way of quickly establishing relationships and getting people to talk and think together.
Stores feature mannequins with exaggerated hips and breasts to sell clothes. Social media delivers more ‘likes’ and praise in a few minutes than we could ever get in the office or at home. Online porn splices together stimulating scenes at a rate that would be impossible to replicate in real life.
I’m just saying that I like a girl who can make me laugh, that’s all. Someone I have fun with no matter what we’re doing.
For someone my size, that maximum amount would be nearly 300 grams per day, or the equivalent of seven or eight chicken breasts.
Experience told me all I had to do was keep him talking and he’d come around. The same way I’d get back whatever I put out, he was getting back whatever he was putting out, so I was with him on this.
Despite well over $100 billion spent on research via the National Cancer Institute, plus many billions more from private industry and public charities—despite all the pink ribbons and yellow bracelets, and literally millions of published papers on the PubMed database—cancer is the second leading cause of death in the United States, right behind heart disease.
The problems of space war that exist at every time scale lie at the intersection of Newton’s laws and human nature.
I visualize my distress tolerance as a window that opens and closes vertically. The narrower this window becomes, the more likely I am to become dysregulated.
Overall, I like to keep average glucose at or below 100 mg/dL, with a standard deviation of less than 15 mg/dL. These are aggressive goals: 100 mg/dL corresponds to an HbA1c of 5.1 percent, which is quite low. But I believe that the reward, in terms of lower risk of mortality and disease, is well worth it given the ample evidence in nondiabetics and diabetics alike.
The small but critical mistake this commits is denying the negative. That actually gives it credence.
We rarely think about change this way because everyone is consumed by the end goal. But one push-up is better than not exercising. One minute of guitar practice is better than none at all. One minute of reading is better than never picking up a book.
It is the cardinal difference between gift and commodity exchange that a gift establishes a feeling-bond between two people.
behind the table or Level II players, 171–72, 186 pronoun usage and, 179, 187 questions to identify, 256