926 quotes from books that matter
Light is the enemy of sleep, full stop. Thus, you want to make your bedroom itself as dark as possible—installing room-darkening curtains if you live somewhere with a lot of outdoor evening light, and removing all light sources in the bedroom, even down to electronic equipment like TVs and cable boxes and such.
We don’t really know, and we are unlikely to find out anytime soon because only about 5 to 8 percent of US cancer research funding goes to the study of metastasis.
One of the key things Beth taught me is that a deadlift is as much about feet and hands as hamstrings and glutes.
Not everyone fits exactly into one of these three types, but many of us will recognize at least some of these traits in ourselves.
Building better habits isn’t about littering your day with life hacks. It’s not about flossing one tooth each night or taking a cold shower each morning or wearing the same outfit each day. It’s not about achieving external measures of success like earning more money, losing weight, or reducing stress.
The best strategy to target cancer is likely by targeting multiple vulnerabilities of the disease at one time, or in sequence.
The strange thing from today’s vantage is how much the world has changed while the law has stayed the same.
The greatest obstacle to accurately identifying someone else’s style is what I call the “I am normal” paradox. That is, our hypothesis that the world should look to others as it looks to us.
I take a very hard line on lowering apoB, the particle that causes all this trouble. (In short: get it as low as possible, as early as possible.)
People who are high in neuroticism tend to be anxious and worry more than others. This trait has been linked to hypersensitivity of the amygdala, the portion of the brain responsible for noticing threats.
Healthy mitochondria are also important to maintaining the health of our brain, and to controlling potential bad actors like oxidative stress and inflammation.
The best we can hope for is reducing our uncertainty. A good experiment in biology only increases or decreases our confidence in the probability that our hypothesis is true or false.
It appears, then, that the presence of amyloid-beta plaques may be neither necessary for the development of Alzheimer’s disease nor sufficient to cause it.
People are more likely to take action at those times because hope is usually higher. A fresh start feels motivating.
Going out of your comfort zone, doing something that is unfamiliar or uncomfortable, is the only way you can hope to change.
Playing came naturally to all of us as kids. Then, somewhere along the way, some of us decided we had more serious and important things to do with ourselves and so we gave up play.
Once I got a little older, knowing how to fall safely, and knowing I knew how to fall safely, opened up a lot of possibilities—for falling for fun!
The one thing that I had in common with some of my patients was that we all found it easier to just avoid dealing with problems that seemed so complex and overwhelming.
Once our habits become automatic, we stop paying attention to what we are doing.
We humans have a unique capacity for turning calories from fructose into fat.
The first step to changing bad habits is to be on the lookout for them. If you feel like you need extra help, then you can try Pointing-and-Calling in your own life.
God grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference.
So before you do anything in the gym, I would urge you to read the next chapter, to begin to understand the crucial and complex concept of stability.
The key is to find an activity that fits into your lifestyle, that you enjoy doing, and that enables you to work at a steady pace that meets the zone 2 test: You’re able to talk in full sentences, but just barely.